Publications

Mapping thalamic innervation to individual L2/3 pyramidal neurons and modeling their ‘readout’ of visual input
Balcioglu A, Gillani R, Doron M, Burnell K, Ku T, Erisir A, Chung K, Segev I, Nedivi E.
Nature Neuroscience. 02 Feb 2023. doi:https://doi.org/10.1038/s41593-022-01253-9 View PDF»

Epitope-preserving magnified analysis of proteome (eMAP)
Park J, Khan S, Yun DH, Ku T, Villa KL, Lee JE, Zhang Q, Park J, Feng G, Nedivi E, Chung K.
Science Advances. 12 Nov 2020; 7(46):eabf6589. doi:10.1101/2020.08.23.263681. View PDF»

Neuron class–specific responses govern adaptive myelin remodeling in the neocortex
Yang SM, Michel K, Jokhi V, Nedivi E, Arlotta P.
Science. 18 Dec 2020; 370(6523). doi:10.1126/sciadv.abf6589. View PDF»

Glutamate Receptors: Not Just for Excitation
Villa KL, Nedivi E.
Neuron. 2019 Dec 18 (104). View PDF»

CPG15/Neuritin mimics experience in selecting excitatory synapses for stabilization by facilitating PSD95 recruitment
Subramanian J, Michel K, Benoit M, Nedivi E.
Cell Reports. 2019 Aug 6;28(6):1584-1595.e5. View PDF»

Genetic variants in the bipolar disorder risk locus SYNE1 that affect CPG2 expression and protein function 
Rathje M, Waxman H, Benoit M, Tammineni P, Leu C, Loebrich S, Nedivi E.
Molecular Psychiatry. 2019 Jan 4, doi: 10.1038/s41380-018-0314-z. View PDF»

Interneuron Simplification and Loss of Structural Plasticity As Markers of Aging-Related Functional Decline
Eavri R, Shepherd J, Welsh CA, Flanders GH, Bear MF, Nedivi E.
Journal of Neuroscience. 2018. 38(39):8421-8432.  View PDF»

Functional implications of inhibitory synapse placement on signal processing in pyramidal neuron dendrites
Boivin JR, Nedivi E.
Current Opinion in Neurobiology. 2018. 51:16-22.  View PDF»

Spine Dynamics: Are They All the Same?
Berry KP, Nedivi E.
Neuron. 2017. 96(1):43-55. View PDF»

Experience-Dependent Structural Plasticity in the Visual System
Berry KP, Nedivi E.
Annu. Rev. Vis. Sci. 2016. 2:17–35.  View PDF» PubMed Link»

Excitatory and Inhibitory Synaptic Placement and Functional Implications
Villa KL, Nedivi E.
K. Emoto et al., Dendrites, Chapter 18. View PDF»

Filling the (SR)GAP in Excitatory/Inhibitory Balance
Subramanian J, Nedivi E.
Neuron Previews. 2016 July 20; 91: 205-207. PubMed Link» View PDF»

Inhibitory Synapses Are Repeatedly Assembled and Removed at Persistent Sites In Vivo.
Villa KL, Berry KP, Subramanian J, Cha JW, Kwon HB, Kubota Y, So PTC, Nedivi E.
Neuron. 2016 Feb 17; 86: 756-769. PubMed Link» View PDF»

CPG2 Recruits Endophilin B2 to the Cytoskeleton for Activity-Dependent Endocytosis of Synaptic Glutamate Receptors.
Loebrich S, Benoit MR, Konopka JA, Cottrell JR, Gibson J, Nedivi E.
Curr Biol. 2016 Jan 12. pii: S0960-9822(15)01566-3. PubMed Link» View PDF»

Genomic mapping and cellular expression of human CPG2 transcripts in the SYNE1 gene.
Loebrich S, Rathje M, Hager E, Ataman B, Harmin DA, Greenberg ME, Nedivi E.
Mol Cell Neurosci. 2015 Dec 15;71:46-55. PubMed Link» View PDF»

Non-descanned multifocal multiphoton microscopy with a multianode photomultiplier tube.
Cha JW, Yew EY, Kim D, Subramanian J, Nedivi E, So PT.
AIP Adv. 2015 Mar 23;5(8):084802. eCollection 2015. PubMed Link» View PDF»

Spectral-resolved multifocal multiphoton microscopy with multianode photomultiplier tubes.
Cha JW, Tzeranis D, Subramanian J, Yannas IV, Nedivi E, So PT.
Opt Express. 2014 Sep 8;22(18):21368-81. doi: 10.1364/OE.22.021368. PubMed Link»

Reassignment of scattered emission photons in multifocal multiphoton microscopy.
Cha JW, Singh VR, Kim KH, Subramanian J, Peng Q, Yu H, Nedivi E, So PT.
Sci Rep. 2014 Jun 5;4:5153. doi: 10.1038/srep05153. PubMed Link» View PDF»

Aberrant development and plasticity of excitatory visual cortical networks in the absence of cpg15.
Picard N, Leslie JH, Trowbridge SK, Subramanian J, Nedivi E, Fagiolini M.
J Neurosci. 2014 Mar 5;34(10):3517-22. doi: 10.1523/JNEUROSCI.2955-13.2014. PubMed Link» View PDF»

Regulation of glutamate receptor internalization by the spine cytoskeleton is mediated by its PKA-dependent association with CPG2.
Loebrich S, Djukic B, Tong ZJ, Cottrell JR, Turrigiano GG, Nedivi E.
Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4548-56. doi: 10.1073/pnas.1318860110. Epub 2013 Nov 4. PubMed link» View PDF»

Highly specific structural plasticity of inhibitory circuits in the adult neocortex.
Chen JL, Nedivi E.
Neuroscientist. 2013 Aug;19(4):384-93. doi: 10.1177/1073858413479824. Epub 2013 Mar 8. PubMed link» View PDF»

Activity-Regulated Genes and Synaptic Plasticity, In: Cellular Migration and Formation of Neuronal Connections.
Leslie JH, Nedivi E.
Comprehensive Developmental Neuroscience Elsevier Inc., Pages 579-597, ISBN 9780123972668. ScienceDirect link»

Synaptogenesis in the Adult CNS–Neocortical Plasticity, In: Cellular Migration and Formation of Neuronal Connections.
Eavri R, Nedivi E.
Comprehensive Developmental Neuroscience Elsevier Inc., Pages 713-721, ISBN 9780123972668. ScienceDirect link»

Clustered dynamics of inhibitory synapses and dendritic spines in the adult neocortex.
Chen JL, Villa KL, Cha JW, So PT, Kubota Y, Nedivi E.
Neuron. 2012 Apr 26;74(2):361-73. doi: 10.1016/j.neuron.2012.02.030. PubMed link» View PDF»

CPG15 regulates synapse stability in the developing and adult brain.
Fujino T, Leslie JH, Eavri R, Chen JL, Lin WC, Flanders GH, Borok E, Horvath TL, Nedivi E.
Genes Dev. 2011 Dec 15;25(24):2674-85. doi: 10.1101/gad.176172.111. PubMed link» View PDF»

Inhibitory dendrite dynamics as a general feature of the adult cortical microcircuit.
Chen JL, Flanders GH, Lee WC, Lin WC, Nedivi E.
J Neurosci. 2011 Aug 31;31(35):12437-43. doi: 10.1523/JNEUROSCI.0420-11.2011. PubMed link» View PDF»

Activity-regulated genes as mediators of neural circuit plasticity.
Leslie JH1, Nedivi E.
Prog Neurobiol. 2011 Aug;94(3):223-37. doi: 10.1016/j.pneurobio.2011.05.002. Epub 2011 May 12. PubMed link» View PDF»

Structural basis for the role of inhibition in facilitating adult brain plasticity.
Chen JL, Lin WC, Cha JW, So PT, Kubota Y, Nedivi E.
Nat Neurosci. 2011 May;14(5):587-94. doi: 10.1038/nn.2799. Epub 2011 Apr 10. PubMed link» View PDF»

Neuronal structural remodeling: is it all about access? 
Chen JL, Nedivi E.
Curr Opin Neurobiol. 2010 Oct;20(5):557-62. doi: 10.1016/j.conb.2010.06.002. PubMed link» View PDF»

Long-term, high resolution imaging in the mouse neocortex through a chronic cranial window.
Holtmaat A, Bonhoeffer T, Chow DK, Chuckowree J, De Paola V, Hofer S, Hübener M, Keck T, Knott G, Lee WC, Mostany R, Mrsic-Flogel TD, Nedivi E, Portera-Cailliau C, Svoboda K, Trachtenberg JT, Wilbrecht L.
Nat Protoc. 2009;4(8):1128-44. doi: 10.1038/nprot.2009.89. Epub 2009 Jul 16. PubMed link»

The function of activity-related genes in the nervous system.
Loebrich S, Nedivi E.
Physiol Rev. 2009 Oct; 89(4): 1079–1103. doi: 10.1152/physrev.00013.2009. PubMed link» View PDF»

A dynamic zone defines interneuron remodeling in the adult neocortex.
Lee WC, Chen J, Huang H, Leslie J, Amitai Y, So PT, Nedivi E.
Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19968-73. doi: 10.1073/pnas.0810149105. Epub 2008 Dec 9. PubMed link» View PDF»

cpg15 and cpg15-2 constitute a family of activity-regulated ligands expressed differentially in the nervous system to promote neurite growth and neuronal survival.
Fujino T, Wu Z, Lin WC, Phillips MA, Nedivi E.
J Comp Neurol. 2008 Apr 10;507(5):1831-45. doi: 10.1002/cne.21649. PubMed link» View PDF»

Multifocal multiphoton microscopy based on multianode photomultiplier tubes.
Kim KH, Buehler C, Bahlmann K, Ragan T, Lee WC, Nedivi E, Heffer EL, Fantini S, So PT.
Opt Express. 2007 Sep 3;15(18):11658-78. PubMed link» View PDF»

Dynamic Remodeling of Dendritic Arbors in GABAergic Interneurons of Adult Visual Cortex. 
Lee WC, Huang H, Feng G, Sanes JR, Brown EN, So PT, Nedivi E. (2006).
PLoS Biol. 2006 Feb;4(2):e29. Epub 2005 Dec 27. PubMed link» View PDF»

Regulation of cpg15 expression during single whisker experience in the barrel cortex of adult mice. 
Harwell C, Burbach B, Svoboda K, Nedivi E.
J Neurobiol. 2005 Oct;65(1):85-96. PubMed link» View PDF»

Soluble CPG15 expressed during early development rescues cortical progenitors from apoptosis. 
Putz U*, Harwell C*, Nedivi E.
Nat Neurosci. 2005 Mar;8(3):322-31. Epub 2005 Feb 13. PubMed link» View PDF»

CPG2; A brain- and synapse-specific protein that regulates the endocytosis of glutamate receptors. 
Cottrell JR, Borok E, Horvath TL, Nedivi E.
Neuron. 2004 Nov 18;44(4):677-90. PubMed link» View PDF»

Regulation of cpg15 by signaling pathways that mediate synaptic plasticity.
Fujino T, Lee WCA, and Nedivi E.
Mol Cell Neurosci. 2003 Nov;24(3):538-54. PubMed link» View PDF»

Extended plasticity of visual cortex in dark-reared animals may result from prolonged expression of cpg15-like genes.
Lee WCA and Nedivi E.
J Neurosci. 2002 Mar 1;22(5):1807-15. PubMed link» View PDF»

Developmental regulation of CPG15 expression in Xenopus. 
Nedivi E, Javaherian A, Cantallops I, Cline HT.
J Comp Neurol. 2001 Jul 9;435(4):464-73. PubMed link» View PDF»

Molecular analysis of developmental plasticity in neocortex. 
Nedivi E.
J Neurobiol. 1999 Oct;41(1):135-47. PubMed link» View PDF»

Dynamic regulation of cpg15 expression during periods of synaptic remodeling in the mammalian visual system. 
Corriveau R, Shatz CJ and Nedivi E.
J Neurosci. 1999 Sep 15; 19(18): 7999–8008. PubMed link» View PDF»

Promotion of dendritic growth by CPG15, an activity-induced signaling molecule.
Nedivi E, Wu G-Y, Cline HT.
Science. 1998 Sep 18;281(5384):1863-6. PubMed link» View PDF»

Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms. 
Hevroni D, Rattner A, Bundman M, Lederfein D, Gabarah A, Mangelus M, Silverman MA, Kedar H, Naor C, Kornuc M, Hanoch T, Seger R, Theil, L, Nedivi E, Citri Y
J Mol Neurosci. 1998 Apr;10(2):75-98. PubMed link» View PDF»

A set of genes expressed in response to light in the adult cerebral cortex and regulated during development. 
Nedivi E, Fieldust S, Theill L, and Hevroni D.
Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2048-53. PubMed link» View PDF»

Numerous candidate plasticity-related genes revealed by differential cDNA cloning. 
Nedivi E, Hevroni D, Naot D, Israeli D and Citri Y.
Nature. 1993 Jun 24;363(6431):718-22. PubMed link» View PDF»