Katrin MichelPostdoctoral Associate

Education

  • Ph.D. degree in Neuroscience from University of Bonn, Germany

Research interest

I am fascinated by the great variety of plasticity mechanisms at the cellular and molecular level that allows the brain to generate adaptive response to our environment. During my PhD work at Bonn University in Germany I focused on the function of small members of the RIM protein family important regulators of presynaptic neurotransmitter release. In my postdoctoral training in the Nedivi lab I will study molecular changes that occur during plasticity mechanisms locally at the synapse, their consequences on neuronal networks, and ultimately behavioral outcome to understand how environmental changes influence cognitive processes and brain function.

Selected publications

  • Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones. Jung S, Oshima-Takago T, Chakrabarti R, Wong AB, Jing Z, Yamanbaeva G, Picher MM, Wojcik SM, Göttfert F, Predoehl F, Michel K, Hell SW, Schoch S, Strenzke N, Wichmann C, Moser T. Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):E3141-9.
  • The presynaptic active zone: A dynamic scaffold that regulates synaptic efficacy. Michel K, Müller JA, Oprişoreanu AM, Schoch S. Exp Cell Res. 2015 Jul 15;335(2):157-64. Review.
  • RIM3γ and RIM4γ are key regulators of neuronal arborization. Alvarez-Baron E*, Michel K*, Mittelstaedt T, Opitz T, Schmitz F, Beck H, Dietrich D, Becker AJ, Schoch S. J Neurosci. 2013 Jan 9;33(2):824-39. (*equally contributed)